What you need to know when the 49ers (0-3) visit the Arizona Cardinals (1-1):
SITE: University of Phoenix Stadium
KICKOFF: 1:05 p.m.
TV: Fox Ch. 2 (Sam Rosen, David Diehl, Jen Hale)
RADIO: 810AM & 107.7 FM (Ted Robinson, Tim Ryan)
1. Sack Carson Palmer. Unable to record a sack in 2 of 3 games, the 49ers have a great opportunity to disrupt the Cardinals’ pass-oriented offense. Arizona’s line is wounded and weak. The Dallas Cowboys sacked Palmer six times Monday night. Pressure is good, sacks are great. Look for Elvis Dumervil to notch his 100th career sack. DeForest Buckner, Arik Armstead, Solomon Thomas, Eli Harold and Aaron Lynch are on call, too.
2. Win the turnover battle. Brian Hoyer has had a pass intercepted in each of his three starts, and opponents have parlayed those into two touchdowns and a field goal. The Cardinals defense will thrive on any mistakes; just ask Colin Kaepernick, who had four passes intercepted and the first two got returned for touchdowns in a 47-7 loss here in 2015. On the defensive side, Jaquiski Tart has the 49ers’ only interception, so that must improve against Palmer (184 interceptions in 14 seasons).
3. Carlos Hyde’s health. A first-quarter hip injury last game couldn’t keep Carlos Hyde on the sideline as he ran for two touchdowns and 84 yards. But Hyde was limited in practice this past week, and fullback Kyle Juszczyk is coming off a concussion and neck injury. Said center Daniel Kilgore: “The thing we’ve got to be able to do is run the ball on them, and once we get that going, it can open up some better options for us.”
INJURIES: 49ers – linebacker Reuben Foster (ankle), safety Eric Reid (knee), defensive end Pita Taumoepenu (ankle), fullback Kyle Juszczyk (head), safety Jaquiski Tartt (head), linebacker Brock Coyle (head). Cardinals – guard Alex Boone (pectoral), wide receiver John Brown (quadricep), tight end Jermaine Gresham (ribs), left tackle D.J. Humphries (knee), left guard Mike Iupati (tricep), linebacker Chandler Jones (chest), wide receiver J.J. Nelson (hamstring), defensive tackle Robert Nkemdiche (calf) and tackle John Wetzel (biceps).
REFEREE: Tony Corrente
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